The suppressive effect of Mekabu fucoidan on an attachment of Cryptosporidium parvum oocysts to the intestinal epithelial cells in neonatal mice

Autor:	Takeshi Sasahara, Hiroko Maruyama, Minoru Hashimoto, Matsuhisa Inoue, Minoru Tanaka
Rok vydání:	2006
Předmět:	Male animal diseases Antiprotozoal Agents Cryptosporidiosis Ileum Mice Inbred Strains Biology Undaria General Biochemistry Genetics and Molecular Biology Microbiology Cell Line Host-Parasite Interactions chemistry.chemical_compound Mice In vivo Polysaccharides parasitic diseases medicine Cell Adhesion Animals General Pharmacology Toxicology and Pharmaceutics Intestinal Mucosa Cryptosporidium parvum Binding Sites Dose-Response Relationship Drug Fucoidan Plant Extracts Oocysts General Medicine Adhesion Carbohydrate biology.organism_classification Specific Pathogen-Free Organisms Dose–response relationship Disease Models Animal medicine.anatomical_structure chemistry Animals Newborn Cell culture Female
Zdroj:	Life sciences. 80(8)
ISSN:	0024-3205
Popis:	The present study was done to investigate the effects of fucoidan and de-sulfated fucoidan isolated from the sporophyll of Undaria pinnatifida on the C. parvum adhesion to the cultured human intestinal cells and on the C. parvum infection in neonatal mice. The C. parvum adhesion to human Intestinal 407 cells was significantly suppressed by a low dose (1 micro g/ml) of Mekabu fucoidan (1 micro g/ml) (approx. 20.5 oocysts, p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90f6c72cd659b29f741539597d35c6ab https://pubmed.ncbi.nlm.nih.gov/17157323 Zobrazit plný text záznamu Full Text from ScienceDirect