Prevalence and characteristics of isolated nocturnal hypertension in the general population

Autor: Deuk-Young Nah, Ki Chul Sung, Eun-Joo Cho, Sun-Woong Kim, Kyung-Soon Hong, Jung-Ha Lee, Moo-Yong Rhee, Namyi Gu, Je Sang Kim, Chee Hae Kim, Ji-Hyun Kim
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: The Korean Journal of Internal Medicine, Vol 36, Iss 5, Pp 1126-1133 (2021)
The Korean Journal of Internal Medicine
ISSN: 2005-6648
1226-3303
Popis: Background/Aims: Ascertaining the prevalence of isolated nocturnal hypertension (INHT) in the general population and identifying the characteristics of patients with INHT may be important to determine patients who should receive 24- hour ambulatory blood pressure (BP) measurements. This study aimed to evaluate the prevalence and characteristics of INHT in the general population.Methods: Of 1,128 participants (aged 20 to 70 years), we analyzed 823 who had valid 24-hour ambulatory BP measurements and were not on antihypertensive drug treatment.Results: The prevalence of INHT in the study was 22.8%. Individuals with INHT had a higher office, 24-hour, and daytime and nighttime ambulatory systolic and diastolic BPs compared to individuals with sustained day-night normotension. INHT was more prevalent in individuals with masked hypertension (MH) than in those with sustained hypertension (59.8% vs. 15.6%, p < 0.001). Among individuals with INHT, 92.6% had MH. Among individuals with office BP-based prehypertension, 34.5% had both INHT and MH. The prevalence of INHT was highest in individuals with office BP-based prehypertension. INHT was an independent determinant of MH after adjustment for age, sex, body mass index, diabetes, low-density-lipoprotein cholesterol, 24-hour systolic and diastolic BP, systolic and diastolic BP dipping, and systolic and diastolic BP non-dipping.Conclusions: The present study showed that INHT is not uncommon and is a major determinant of MH. Our findings strongly suggest the use of 24-hour ambulatory BP measurement for individuals within the prehypertension range of office BP owing to the high prevalence of INHT and MH in this population.
Databáze: OpenAIRE