Iron-Based Catalyst for Borylation of Unactivated Alkyl Halides without Using Highly Basic Organometallic Reagents

Autor:	Sheema Siddiqui, Ramesh Bhawar, K. Geetharani
Rok vydání:	2020
Předmět:	chemistry.chemical_classification chemistry.chemical_compound chemistry Iron based Reagent Amide Organic Chemistry Polymer chemistry Halide Borylation Alkyl Catalysis Diborane
Zdroj:	The Journal of Organic Chemistry. 86:1948-1954
ISSN:	1520-6904 0022-3263
Popis:	The mild borylation of alkyl bromides and chlorides with bis(neopentylglycolato)diborane (B2neop2) mediated by iron-bis amide is described. The reaction proceeds with a broad substrate scope and good functional group compatibility. Moreover, sufficient catalytic activity was obtained for primary and secondary alkyl halides. Mechanistic studies indicate that the reaction proceeds through a radical pathway.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90e1850fe06cfe25e28d7cc605994ba0 https://doi.org/10.1021/acs.joc.0c02364 Zobrazit plný text záznamu