Contact allergy in children with and without atopic dermatitis: An Italian multicentre study
| Autor: | Bonamonte, Domenico, Hansel, Katharina, Romita, Paolo, Fortina, Anna Belloni, Girolomoni, Giampiero, Fabbrocini, Gabriella, Patruno, Cataldo, Napolitano, Maddalena, Patrizi, Annalisa, Argenziano, Giuseppe, Micali, Giuseppe, Calzavara Pinton, Piergiacomo, Foti, Caterina, Stingeni, Luca, Italian Society of Dermatology and Venereology, Pediatric Dermatology Group: Chiara Barlusconi, Francesco Bellinato, Stefano Caccavale, Giulia Calabrese, Francesca Caroppo, Aurora De Marco, Angela Filoni, Rossella Marietti, Maria Rita Nasca, Iria Neri, Donatella Schena, Marta Tramontana, Annalisa Vascellaro |
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| Přispěvatelé: | Bonamonte, Domenico, Hansel, Katharina, Romita, Paolo, Fortina, Anna Belloni, Girolomoni, Giampiero, Fabbrocini, Gabriella, Patruno, Cataldo, Napolitano, Maddalena, Patrizi, Annalisa, Argenziano, Giuseppe, Micali, Giuseppe, Calzavara Pinton, Piergiacomo, Foti, Caterina, Stingeni, Luca, Italian Society of Dermatology and Venereology, Pediatric Dermatology Group: Chiara Barlusconi, Francesco, Bellinato, Caccavale, Stefano, Giulia, Calabrese, Francesca, Caroppo, Aurora De Marco, Angela, Filoni, Rossella, Marietti, Maria Rita Nasca, Iria, Neri, Donatella, Schena, Marta, Tramontana, Annalisa, Vascellaro, Bonamonte, D., Hansel, K., Romita, P., Fortina, A. B., Girolomoni, G., Fabbrocini, G., Patruno, C., Napolitano, M., Patrizi, A., Argenziano, G., Micali, G., Calzavara Pinton, P., Foti, C., Stingeni, L., Barlusconi, C., Bellinato, F., Caccavale, S., Calabrese, G., Caroppo, F., De Marco, A., Filoni, A., Marietti, R., Nasca, M. R., Neri, I., Schena, D., Tramontana, M., Vascellaro, A. |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
atopic dermatiti
Male Allergic Contact atopic dermatitis children contact allergy patch testing Allergens Child Female Humans Patch Tests Potassium Dichromate Prevalence Retrospective Studies Dermatitis Allergic Contact Dermatitis Atopic Dermatitis Dermatology Atopic Retrospective Studie Immunology and Allergy Patch Test Allergen Contact allergy Human |
| Popis: | Background: Contact allergy and atopic dermatitis (AD) are both common inflammatory T cell-mediated diseases and many factors may influence the prevalence of contact allergy in AD patients. In children, their possible correlation was debated with conflicting results. Objectives: The present study aimed to assess the prevalence of contact sensitivity in children and to investigate the association with AD. Materials and methods: A retrospective multicentre study on children aged from 0 to 14 years patch tested between January 2017 and December 2018 was performed. Children were consecutively patch tested with the SIDAPA (Società Italiana Dermatologia Allergologica Professionale Ambientale) baseline series. Results: Among the 432 children investigated for contact allergy, 125 (28.9%) showed a positive reaction to at least one of the allergens tested, with a higher prevalence of positive patch test reactions in girls (32.3%) than in boys (25.0%). The most frequent contact allergens were nickel sulphate (10.2%), cobalt chloride (6.7%), methylisothiazolinone (3.7%), fragrance mix-2 (3.2%), potassium dichromate (2.8%), fragrance mix-1 (2.1%) and methylchloroisothiazolinone/methylisothiazolinone (2.1%). One-hundred-three children (23.8%) suffered from AD showing a higher prevalence of positive patch test (36.9%) compared to children without AD (26.4%). Conclusions: Despite the topic being still controversial, the present study suggests a consistent prevalence of contact allergy among children with higher sensitivity rate among children with AD than without AD. |
| Databáze: | OpenAIRE |
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