Perfil Químico e Análise Antioxidante in vitro do extrato e fração de Auxemma glazioviana Taub
| Autor: | José Galberto Martins da Costa, Débora Odília Duarte Leite, Carla de Fatima Alves Nonato, Gerson Javier Torres Salazar, Natália Kelly Gomes de Carvalho, Cicera Janaine Camilo, Lucas Ribeiro Costa |
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| Rok vydání: | 2020 |
| Předmět: |
Antioxidant
medicine.medical_treatment Fraction (chemistry) Antioxidant potential 030226 pharmacology & pharmacy 01 natural sciences lcsh:Social Sciences 03 medical and health sciences 0302 clinical medicine medicine Antioxidante Cromatografia lcsh:Science (General) General Environmental Science lcsh:LC8-6691 Auxemma glazioviana lcsh:Special aspects of education biology Traditional medicine 010405 organic chemistry Chemistry Boraginaceae biology.organism_classification 0104 chemical sciences Quinone lcsh:H Antioxidant capacity Phytochemical Polyphenol General Earth and Planetary Sciences Quinonas lcsh:Q1-390 |
| Zdroj: | Research, Society and Development, Vol 9, Iss 10 (2020) |
| ISSN: | 2525-3409 |
| DOI: | 10.33448/rsd-v9i10.9387 |
| Popis: | Auxemma glazioviana Taub. (Boraginaceae), known as "white stick", is distributed in the states of Ceara and Rio Grande do Norte and is traditionally used in the treatment of cuts and wounds. The different biological activities are associated with the presence of quinones, a chemical compound widely occurring in the species. The objective of this study was to identify the main classes of secondary metabolites, quantify the total content of polyphenols, obtain the quinone fraction (FQ) and evaluate the antioxidant potential of the ethanolic extract of A. glazioviana and the fraction obtained. From the extract a phytochemical screening and quantification of total polyphenols was performed. The attainment and characterization of the quinone fraction was done through chromatographic techniques. The antioxidant potential of the extract and of the fraction was determined by the methods, DPPH●; capture of free radical ABTS●+, determination of the reduction power of Fe3+ ion (FRAP) and relative antioxidant capacity (CAR). The chemical prospection of the ethanolic extract revealed the presence of flavonoids. The quantification of total polyphenols was 4.4822 mg AG/g.extract. In the antioxidant analysis, extract and fraction presented significant results, in which EECCAG was more efficient when compared to FQ. The data show that EECCAG is potentially more efficient in antioxidant activity. |
| Databáze: | OpenAIRE |
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