Immunotoxicological impact of occupational and environmental nanoparticles exposure: The influence of physical, chemical, and combined characteristics of the particles
| Autor: | Elpidio Maria Garzillo, Mario Di Gioacchino, Paola Pedata, Claudia Petrarca |
|---|---|
| Přispěvatelé: | Pedata, Paola, Petrarca, Claudia, Garzillo Elpidio, Maria, Di Gioacchino, Mario |
| Rok vydání: | 2016 |
| Předmět: |
inorganic chemicals
0301 basic medicine Immunology Nanoparticle Nanotechnology 02 engineering and technology Cellular level Toxicology 03 medical and health sciences Physical chemical mental disorders Humans Immunology and Allergy health care economics and organizations Exposure assessment Pharmacology Immunotoxins Editorials technology industry and agriculture Environmental Exposure Environmental exposure respiratory system 021001 nanoscience & nanotechnology Applications of nanotechnology 030104 developmental biology Nanoparticles Environmental science Public Health Occupational exposure 0210 nano-technology environmental exposure health effects immunotoxicity nanoparticle exposure occupational exposure |
| Zdroj: | International Journal of Immunopathology and Pharmacology. 29:343-353 |
| ISSN: | 2058-7384 |
| DOI: | 10.1177/0394632015608933 |
| Popis: | While nanotechnology is growing exponentially, the knowledge of the impact of nanoparticles (NPs) on public health and the environment is limited so far. Current nanomaterial research is focused on the applications of nanotechnology, whereas there is little information on exposure assessment and risk characterization associated with NPs. Therefore, it is essential that the factors influencing NPs associated hazards be studied. This review seeks to survey and evaluate the current literature in order to better understand the impact of both airborne and engineered NPs exposure, the mechanisms at the cellular level, and the factors influencing their immunotoxicity. In fact, NPs do have immunotoxicological significance, as immune cells in the bloodstream and tissues do act to eliminate or interact with NPs. Proper characterization of the NPs as well as understanding the processes occurring on the NPs surface when in contact with biological systems is crucial to predict or exclude toxicological effects. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|