The spectrum of mutations at the p53 locus. Evidence for tissue-specific mutagenesis, selection of mutant alleles, and a 'gain of function' phenotype
| Autor: | Abigail L Silver, Anwell Chang, Michael C. Wu, Arnold J. Levine, Edward F. Attiyeh, Charles B. Epstein, Jiayuh Lin |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Male
Xenopus Molecular Sequence Data Locus (genetics) Biology General Biochemistry Genetics and Molecular Biology Frameshift mutation Mice History and Philosophy of Science Neoplasms Animals Humans Point Mutation Amino Acid Sequence Allele Codon Frameshift Mutation Gene Alleles Genetics Sequence Homology Amino Acid General Neuroscience Point mutation Chromosome Mapping Genes p53 Phenotype Sequence homology Mutagenesis Organ Specificity Mutation Female Tumor Suppressor Protein p53 Chromosomes Human Pair 17 |
| Zdroj: | Annals of the New York Academy of Sciences. 768 |
| ISSN: | 0077-8923 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text