Bone formation using human demineralised bone matrix (Grafton) for the treatment of bone cysts in children
| Autor: | Kroker S, Hass Hj, W. Wagemann, Meyer F, Hardy Krause |
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| Rok vydání: | 2007 |
| Předmět: |
Glycerol
Male medicine.medical_specialty Adolescent Bone matrix Cystic lesion Osteogenesis Enchondroma medicine Bone Cysts Humans Bone formation Child Bone cyst Retrospective Studies business.industry dBm medicine.disease Surgery Treatment Outcome Child Preschool Pediatrics Perinatology and Child Health Cyst formation Female Bone Remodeling Pathological fractures business |
| Zdroj: | European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie. 17(1) |
| ISSN: | 0939-7248 |
| Popis: | Bone cysts, in particular solitary bone cysts, are the most frequent cause of pathological fractures in children. However, there is still a great variety of regimens used to treat these lesions. Since demineralised bone matrix (DBM) is commercially available, we aimed to use this material for the consolidation of bones diagnosed as fragile because of cyst formation. Each of the 7 bone cysts as well as one enchondroma filled with DBM showed a continuous decrease in bone transparency over a period of two years (mean 8 months). A significant decrease in bone transparency and simultaneous cortical remodelling was radiographically detected in these cases as the specific hallmark of an initiated graft incorporation after 3 to 4 months. It was demonstrated that it is possible to heal children within an acceptable period of time using DBM to fill the cystic lesion. DBM appears to be a reasonable and beneficial alternative for the treatment of bone cysts offering both osteoinduction and osteoconductive features. |
| Databáze: | OpenAIRE |
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