Diffuse plane xanthomatosis associated with a monoclonal band displaying anti-smooth muscle antibody activity
| Autor: | P. C. Sharpe, M. J. O'kane, D. P. Nicholls, S.A. Mcmillan, J.F. Dawson, M.Y. Walsh |
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| Rok vydání: | 1995 |
| Předmět: |
Electrophoresis
Pathology medicine.medical_specialty Dermatology Xanthoma Diffuse plane xanthomatosis Monoclonal Band Immunopathology Xanthomatosis Medicine Humans Autoantibodies Skin biology medicine.diagnostic_test business.industry Muscle Smooth Middle Aged Muscle antibody medicine.disease Liver biopsy Face Axilla biology.protein Anti-smooth muscle antibody Female Antibody business Neck |
| Zdroj: | The British journal of dermatology. 133(6) |
| ISSN: | 0007-0963 |
| Popis: | We report a patient with diffuse planar xanthomatous lesions associated with a benign monoclonal gammopathy. This patient has a very high titre of anti-smooth muscle antibody (1 :10,240), but normal liver function tests and a normal liver biopsy. The paraprotein band displays anti-smooth muscle antibody activity. There is no evidence of any other underlying disease process. The findings are consistent with a diagnosis of diffuse plane xanthomatosis, but the mechanism of xanthoma formation remains unclear. |
| Databáze: | OpenAIRE |
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