The efficacy of povidone-iodine products against periodontopathic bacteria
| Autor: | Tomohisa Ogawa, Kazuyuki Ishihara, Yasuo Hosaka, Taneaki Nakagawa, Kyuichi Kamoi, Soh Sato, Toru Hiraishi |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
medicine.drug_class
Dermatology Aggregatibacter actinomycetemcomitans Prevotella intermedia Microbiology Antiseptic Gram-Negative Bacteria medicine Humans Porphyromonas gingivalis Povidone-Iodine Mouth biology Fusobacterium nucleatum Chemistry Chlorhexidine biology.organism_classification stomatognathic diseases Streptococcus anginosus Actinobacillus Anti-Infective Agents Local Bacteria medicine.drug |
| Zdroj: | Dermatology (Basel, Switzerland). 212 |
| ISSN: | 1018-8665 |
| Popis: | A total of 8 strains of 6 bacterial species, Porphyromonas gingivalis ATCC33277 and TDC286, Actinobacillus actinomycetemcomitans ATCC29523 and JP2, Fusobacterium nucleatum No. 2, Tannerella forsythensis ATCC43937, Prevotella intermedia ATCC25611 and Streptococcus anginosus ATCC33397, were treated with povidone-iodine (PVP-I) gargle (PVP-I: 0.47 and 0.23% w/v) or chlorhexidine gluconate (CHG) gargle (CHG: 0.002% w/v) for 15, 30 or 60 s, after which they were inoculated into various media, cultured and counted for residual bacteria. At both concentrations, PVP-I gargle reduced the viable cell count of all 8 bacterial strains to below the measurable limit within 15 s. By contrast, there were more than 1,000 viable colonies 60 s following treatment with the CHG gargle. The results demonstrate that povidone-iodine gargle has rapid bactericidal activity against the causative bacteria of periodontal disease. |
| Databáze: | OpenAIRE |
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