Exploratory study on cognitive abilities and social responsiveness in children with 22q11.2 deletion syndrome (22q11DS) and children with idiopathic intellectual disability (IID)
| Autor: | Ellen Van Den Heuvel, Inge Zink, Ellen Rombouts, Evi Jonkers, Ann Swillen, Eric Manders |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
Developmental trajectories Social Sciences Neuropsychological Tests PHENOTYPE Developmental psychology Child Development Cognition 0302 clinical medicine Intellectual disability ADOLESCENTS Developmental and Educational Psychology Social responsiveness Child AUTISM SPECTRUM CARDIO-FACIAL-SYNDROME 05 social sciences Rehabilitation Clinical Psychology VELOCARDIOFACIAL SYNDROME Autism spectrum disorder Education Special Female Psychology Life Sciences & Biomedicine 050104 developmental & child psychology Population Exploratory research SPECTRUM DISORDERS PROFILE Social Skills 03 medical and health sciences PSYCHOSIS Social skills Intellectual Disability DiGeorge Syndrome medicine Humans Idiopathic intellectual disability 0501 psychology and cognitive sciences Cognitive skill Monitoring Physiologic LEARNING-DISABILITY Science & Technology Cognitive abilities medicine.disease Education & Educational Research 22q11.2 deletion syndrome 030217 neurology & neurosurgery Strengths and weaknesses MENTAL-RETARDATION |
| Popis: | BACKGROUND: Development of cognitive skills and social responsiveness are areas of concern in children with 22q11.2 deletion syndrome (22q11DS). It remains unclear if the cognitive and social profiles and trajectories are syndrome-specific or similar to those of children with idiopathic intellectual disabilities (IID) with or without comorbid autism spectrum disorder (ASD). AIMS AND METHODS: In this exploratory study, we examined and compared five broad cognitive abilities (BCAs) and the social responsiveness in primary school-aged children with 22q11DS (age 6-13, n = 21) and IQ-matched peers with IID (n = 21). The relative strengths and weaknesses of both groups were re-evaluated after 19 to 30 months. OUTCOMES AND RESULTS: Four different cognitive trajectories (i.e. absolute progress, stability, growing into deficit, and absolute decline) were demonstrated in both groups. Most children showed combined types of trajectories across BCAs resulting in a complex changing cognitive profile. In the 22q11DS group, social responsiveness problems increased, whereas no significant change was observed in the IID group. CONCLUSIONS AND IMPLICATIONS: Results reflect similar cognitive and social responsiveness profiles and trajectories across groups with children with 22q11DS being more at risk for growing into a social deficit. We recommend repeated monitoring of social skills development to adapt the environmental demands to the child's individual social capacities. ispartof: RESEARCH IN DEVELOPMENTAL DISABILITIES vol:81 pages:89-102 ispartof: location:United States status: published |
| Databáze: | OpenAIRE |
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