Adenoma Detection before and after the age of 50: a retrospective analysis of Lebanese outpatients
| Autor: | Mohammed Hussein Kamareddine, Anwar Andrew Nader, Karam Karam, Ahmad El-Mahmoud, Youssef Ghosn, Said Farhat, Naseem Bou-Ayash, Mansour El-Khoury |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Adenoma Colorectal cancer Population Colonoscopy colon carcinogenesis 03 medical and health sciences 0302 clinical medicine colonoscopy Internal medicine Biopsy medicine Outpatient clinic colonic adenomas education Colorectal Cancer education.field_of_study medicine.diagnostic_test business.industry Incidence (epidemiology) Gastroenterology colonic neoplasms medicine.disease Ulcerative colitis digestive system diseases 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology business |
| Zdroj: | BMJ Open Gastroenterology |
| ISSN: | 2054-4774 |
| Popis: | Background and aimColorectal cancer (CRC) has an increased impact on the Lebanese population’s morbidity and mortality. This study evaluated the situation of adenoma detection in an outpatient clinic in Lebanon.Patients and methods918 patients underwent colonoscopy over a period of 24 months by a qualified physician. Biopsy results were divided into normal versus abnormal colonic tissue, which was further subdivided into number of polyps and cancer.ResultsOut of 918 individuals included, 82 cases of Crohn’s colitis (8.93%) and 22 cases of ulcerative colitis (2.39%) were identified. A total of 42 cases of CRC (4.58%) and 188 cases of adenomatous polyps (20.48%) were identified. The data show that age >50 years and male gender significantly correlate with increased incidence of precancerous and cancerous polyps. Further exploring the results by age groups and gender, detection of adenomatous polyps in women aged 40–49 (8.33%) was significantly different from their female counterparts aged ≥50 years old (25.26%) (pConclusionWithin the limitations of this study, the incidence of CRC and adenomatous polyps falls in the high range compared with international studies. Furthermore, symptomatic male patients aged 40–49 appear to exhibit detection rates of adenomas similar to their counterparts aged ≥50 years old. Subjects younger than 50 years underwent diagnostic rather than screening colonoscopy, which introduces some selection bias. Nevertheless, these findings can serve as a basis for further studies. |
| Databáze: | OpenAIRE |
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