A label-free lateral offset spliced coreless fiber MZI biosensor based on hydrophobin HGFI for TNF-α detection

Autor:	Bo Wang, Shaoxiang Duan, Hao Zhang, Haijin Xu, Bo Liu, Mingqiang Qiao
Rok vydání:	2022
Předmět:	Electrical and Electronic Engineering Condensed Matter Physics Atomic and Molecular Physics and Optics Electronic Optical and Magnetic Materials
Zdroj:	Optoelectronics Letters. 18:263-268
ISSN:	1993-5013 1673-1905
DOI:	10.1007/s11801-022-2061-2
Popis:	A real-time label-free lateral offset spliced coreless fiber (CF) Mach-Zehnder interferometer (MZI) biosensor functionalized with hydrophobin Grifola frondosa I (HGFI) was proposed for the detection of cytokine tumour necrosis factor alpha (TNF-α). The nanolayer self-assembled on the optical fiber surfaces by HGFI rendered the immobilization of probe TNF-α antibody and recognition of antigen TNF-α. Trifluoroacetic acid was utilized to remove the HGFI layer from the glass surface, which was validated by field emission scanning electron microscopy (FESEM) and water contact angle (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90cacd799ffa70eb595de9020040fe16 https://doi.org/10.1007/s11801-022-2061-2 Zobrazit plný text záznamu Full text from SpringerLink