Relationship Between Dynamic Expiratory Time Constant τedyn and Parameters of Breathing Cycle in Pressure Support Ventilation Mode
| Autor: | P Török, P Candik, D Rybár, František Sabol, V Donic, F Depta, S Imrecze, V Doničová, K Galková, A Kolesar, M Nosáľ |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Physiology Pressure support ventilation 030204 cardiovascular system & hematology Positive-Pressure Respiration 03 medical and health sciences Work of breathing 0302 clinical medicine Internal medicine medicine Humans Respiratory system Aged Retrospective Studies Physics Expiratory Time Respiratory center 030208 emergency & critical care medicine General Medicine Breathing cycle Middle Aged Respiration Artificial Exhalation Respiratory Mechanics Cardiology Breathing Female Constant (mathematics) Ventilator Weaning |
| Zdroj: | Physiological Research. :875-879 |
| ISSN: | 1802-9973 0862-8408 |
| DOI: | 10.33549/physiolres.933750 |
| Popis: | Study of the relationship between ventilation parameters: monitored expiratory time constant - tau(edyn) and breathing - trigger frequency (f(trig)) and time of breathing cycle (T(cy)) are main goals of this article. Parameters were analyzed during last 4+/-2 h before weaning from ventilation in 66 patients ventilated in pressure support mode (PSV). We have found out, that there exist mathematical relationships, observed during adequate gas exchange, yet not described. Monitored parameters are represented by tau(edyn), f(trig) and T(cy). The analysis showed close negative correlation between T(cy) and f(trig) (R(2)=0.903). This implies that each increasing of tau(edyn) causes decreasing of f(trig) and vice versa. The calculation of regression equation between tau(edyn) and T(cy) outlined that T(cy) = 5.2625 * tau(edyn) + 0.1242 (R(2)=0.85). Regulation of respiratory cycles by the respiratory center in the brain is probably based on evaluation of tau(edyn) as the tau(edyn) probably represents a regulatory element and T(cy) regulated element. It can be assumed, that respiratory center can optimize the work of breathing in order to minimize energy in system patient + ventilator. The unique relationship, described above could be useful in clinical practice for development of new ventilation modes. |
| Databáze: | OpenAIRE |
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