Three-dimensional analysis of cortical bone structure using X-ray micro-computed tomography

Autor: Holger Averdunk, Christoph H. Arns, Adrian Sheppard, Bruce Milthorpe, Anthony C. Jones, Mark Knackstedt, Arthur Brandwood, Robert Sok, Ajay Limaye, Arthur Sakellariou, Timothy Senden
Rok vydání: 2004
Předmět:
Zdroj: Physica A: Statistical Mechanics and its Applications. 339:125-130
ISSN: 0378-4371
DOI: 10.1016/j.physa.2004.03.046
Popis: We demonstrate the capability of X-ray micro-computed tomography to image the micro-structure of human cortical bone. At 5 μm voxel size we observe the complex morphology of the Haversian network in three dimensions. The local thickness of Haversian canals is measured using a maximal sphere algorithm and found to have a bimodal signature and a mean radius of 19.2 μm. The intra-cortical porosity due to Haversian canals is measured as 3.0%. Both results are in agreement with traditional histomorphometric measurements. We show that at higher resolutions one can resolve the spatial distribution of lacunae in cortical bone. © 2004 Elsevier B.V. All rights reserved.
Databáze: OpenAIRE