Maltoma of the Thyroid and Sjögren's Syndrome in a Woman with Hashimoto's Thyroiditis
| Autor: | Andreas C. Lazaris, Margarita Anapliotou, Thomas Paterakis, Thomas G. Papathomas, Athina Androulaki, Dimitrios Pikazis, Vassiliki Syriou |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
endocrine system
Pathology medicine.medical_specialty endocrine system diseases Endocrinology Diabetes and Metabolism Hashimoto Disease Anorexia Thyroiditis Pathology and Forensic Medicine Diagnosis Differential Endocrinology immune system diseases hemic and lymphatic diseases Biomarkers Tumor Humans Medicine Thyroid Neoplasms Aged business.industry Thyroid MALT lymphoma Lymphoma B-Cell Marginal Zone General Medicine medicine.disease Dermatology Lymphoma Thyroxine Sjogren's Syndrome medicine.anatomical_structure Etiology Female Sjogren s medicine.symptom business Lymphocytic Thyroiditis |
| Zdroj: | Endocrine Pathology. 17:89-94 |
| ISSN: | 1046-3976 |
| DOI: | 10.1385/ep:17:1:89 |
| Popis: | We report the case of a 70-yr-old woman with maltoma of the thyroid, Sjögren's syndrome, and a history of Hashimoto's thyroiditis. The patient underwent a total thyroidectomy for a recently growing mass of the thyroid, while being treated with L-thyroxine for Hashimoto's thyroiditis. Postoperatively, routine histologic examination was consistent with the diagnosis of chronic lymphocytic thyroiditis of autoimmune etiology. Three years later, the patient presented with high temperature, anorexia, and coughing. This time, a microscopic examination of deeper thyroid tissue sections and an immunohistochemical study revealed a low-grade, non-Hodgkin lymphoma, MALT type. Simultaneously, the diagnosis of Sjögren's syndrome was established and the patient is currently under investigation for generalized lymphoma. This case clearly demonstrates the difficulty in differentially diagnosing Hashimoto's thyroiditis from low-grade MALT lymphoma by the use of routine histologic examination. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink