Reduced Systolic Volume: Main Pathophysiological Mechanism in Patients with Orthostatic Intolerance?
| Autor: | Adriano Magajevski, Niraj Mehta, Maria Zildany Pinheiro Távora-Mehta, Débora Lee Smith Maluf, Eduardo Doubrawa, Claudio Da Cunha, Marcio Rogério Ortiz, Larissa de Oliveira, Letícia Concato |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
lcsh:Diseases of the circulatory (Cardiovascular) system
Supine position Time Factors Hemodynamics Orthostatic intolerance Blood Pressure 030204 cardiovascular system & hematology Tilt table test Orthostatic vital signs 0302 clinical medicine Reference Values Tilt-Table Test Supine Position Medicine Aged 80 and over Postural Orthostatic Tachycardia Syndrome/physiopathology medicine.diagnostic_test Anthropometry Middle Aged Intolerância Ortostática/fisiopatologia medicine.anatomical_structure Síndrome da Taquicardia Postural Ortostática/fisiopatologia Anesthesia medicine.symptom Resistência Vascular Cardiology and Cardiovascular Medicine Adult Adolescent Systole Asymptomatic Syncope Orthostatic Intolerance/physiopathology 03 medical and health sciences Young Adult 030225 pediatrics Humans Aged Retrospective Studies business.industry Stroke Volume Original Articles medicine.disease Tilt Test Blood pressure lcsh:RC666-701 Case-Control Studies Vascular resistance Orthostatic Intolerance Vascular Resistance business Volume Sistólico |
| Zdroj: | Arquivos Brasileiros de Cardiologia, Volume: 107, Issue: 4, Pages: 354-364, Published: OCT 2016 Arquivos Brasileiros de Cardiologia, Vol 107, Iss 4, Pp 354-364 Arquivos Brasileiros de Cardiologia v.107 n.4 2016 Arquivos Brasileiros de Cardiologia Sociedade Brasileira de Cardiologia (SBC) instacron:SBC |
| Popis: | Background: Orthostatic intolerance patients' pathophysiological mechanism is still obscure, contributing to the difficulty in their clinical management. Objective: To investigate hemodynamic changes during tilt test in individuals with orthostatic intolerance symptoms, including syncope or near syncope. Methods: Sixty-one patients who underwent tilt test at - 70° in the phase without vasodilators were divided into two groups. For data analysis, only the first 20 minutes of tilting were considered. Group I was made up of 33 patients who had an increase of total peripheral vascular resistance (TPVR) during orthostatic position; and Group II was made up of 28 patients with a decrease in TPVR (characterizing insufficient peripheral vascular resistance). The control group consisted of 24 healthy asymptomatic individuals. Hemodynamic parameters were obtained by a non-invasive hemodynamic monitor in three different moments (supine position, tilt 10' and tilt 20') adjusted for age. Results: In the supine position, systolic volume (SV) was significantly reduced in both Group II and I in comparison to the control group, respectively (66.4 ±14.9 ml vs. 81.8±14.8 ml vs. 101.5±24.2 ml; p |
| Databáze: | OpenAIRE |
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