Absence of mutagenic activity in the bacterial reverse mutation assay with pulegone and peppermint oil
| Autor: | Maodo Malick Diop, Christie L. Harman, Christopher Choi, Cody L Wilson, Sylvain Etter, Heidi Bialk, Xing Han, Michel Aubanel, Gerhard Krammer, Jan Demyttenaere, Sean V. Taylor, Maria Bastaki, Vivian Lu, Jürgen Schnabel |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0106 biological sciences
0303 health sciences Chemistry food and beverages 01 natural sciences Reverse mutation law.invention Ames test 03 medical and health sciences chemistry.chemical_compound law lcsh:RA1190-1270 Food science Pulegone Essential oil 030304 developmental biology 010606 plant biology & botany lcsh:Toxicology. Poisons |
| Zdroj: | Toxicology Research and Application, Vol 4 (2020) |
| ISSN: | 2397-8473 |
| Popis: | The essential oil of peppermint and one of its natural constituents, (R)-(+)-pulegone, are approved flavorings added to food worldwide. (R)-(+)-Pulegone and peppermint oil were tested separately in two independent bacterial reverse mutation assays according to Organisation for Economic Co-operation and Development Guideline 471. Both flavorings did not produce any evidence of mutagenicity up to cytotoxic concentrations in either the presence or the absence of exogenous metabolic activation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|