Impact of the bacterial nasopharyngeal microbiota on the severity of genus enterovirus lower respiratory tract infection in children: a case–control study
| Autor: | Daniel Penela-Sánchez, Muntsa Rocafort, Desiree Henares, Iolanda Jordan, Pedro Brotons, María Cabrerizo, Cristian Launes, Carmen Muñoz-Almagro |
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| Přispěvatelé: | Instituto de Salud Carlos III, Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF) |
| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: |
Pulmonary and Respiratory Medicine
Unidades de cuidados intensivos Intensive care units Bacteria Rhinovirus Infecció del tracte respiratori inferior Microbiota Infant Infección del tracto respiratorio inferior Lower respiratory tract infection Cross-Sectional Studies Case-Control Studies RNA Ribosomal 16S Pediatrics Perinatology and Child Health Viruses Enterovirus Infections Humans Child Respiratory Tract Infections Unitats de cures intensives Rinovirus Enterovirus |
| Popis: | Introduction: Rhinoviruses (RV) and enteroviruses (EV) are among the main causative etiologies of lower respiratory tract infection (LRTI) in children. The clinical spectrum of RV/EV infection is wide, which could be explained by diverse environmental, pathogen-, and host-related factors. Little is known about the nasopharyngeal microbiota as a risk factor or disease modifier for RV/EV infection in pediatric patients. This study describes distinct nasopharyngeal microbiota profiles according to RV/EV LRTI status in children. Methods: Cross-sectional case-control study, conducted at Hospital Sant de Déu (Barcelona, Spain) from 2017 to 2020. Three groups of children |
| Databáze: | OpenAIRE |
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