Effect of urea and tmao on lipid bilayers
Autor: | J. Valerio, S. Bernstorff, S.S. Funari |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
0301 basic medicine
technology industry and agriculture RM1-950 010402 general chemistry 01 natural sciences 0104 chemical sciences 03 medical and health sciences chemistry.chemical_compound lipid membranes - phase transitions - osmocytes - x-rays - dsc 030104 developmental biology chemistry Biochemistry Urea lipids (amino acids peptides and proteins) Therapeutics. Pharmacology General Pharmacology Toxicology and Pharmaceutics Lipid bilayer |
Zdroj: | European Pharmaceutical Journal, Vol 64, Iss 2, Pp 24-27 (2017) |
ISSN: | 2453-6725 |
Popis: | We study the effect of the osmolytes, Urea and trimethylamine-N-oxide (TMAO) on POPE (1-palmitoyl-2-oleoyl-sn-glycero-3- phosphoethanolamine) lipid membranes using SAXS/WAXS and DSC. Their antagonist effect is observed with TMAO stabilizing and Urea destabilizing the lipid bilayer, as seen by others in earlier researches. |
Databáze: | OpenAIRE |
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