Cytomegalovirus infection of the uterine cervix: Local cervical infection and antibody response
| Autor: | Wey Siong Tsai, Ping Yen Wei, Wen Tsuo Chiang, Hong-Ming Chen, E. Russell Alexander, Chang-Yao Hsieh |
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| Rok vydání: | 1981 |
| Předmět: |
medicine.medical_specialty
Pathology Biopsy Congenital cytomegalovirus infection Cytomegalovirus Papanicolaou stain Cervix Uteri Antibodies Viral Gastroenterology Uterine Cervical Diseases Internal medicine Metaplasia medicine Humans Vaginal Smears Colposcopy medicine.diagnostic_test business.industry Carcinoma in situ Obstetrics and Gynecology General Medicine medicine.disease Body Fluids Titer Cytomegalovirus Infections Female Culdoscopy medicine.symptom business Papanicolaou Test |
| Zdroj: | International Journal of Gynecology & Obstetrics. 19:177-180 |
| ISSN: | 0020-7292 |
| Popis: | Thirty-three women were examined on three or more occasions, each at 2-month intervals. The overall recovery rate of cytomegalovirus (CMV) was 28% (60/215). CMV was recovered from 53% of the cases where the local antibody was 1 : 64 or greater but the greatest difference occurred below titers of 1 : 32. Below that level virus was recovered in less than 5%, compared to a prevalence of 35% for cases with a titer of 1 : 32 (P less than 0.001). Twenty-eight cases in whom CMV was sought underwent colposcopy examination and had cytologic smears examined by the papanicolaou method. The external uterine cervix with columnar cells only yield a CMV prevalence of 3/17 (18%). However, if colposcopy showed either atypical transformation or metaplasia the prevalence was 4/11 (36%). Similarly, it is provocative that the prevalence of CMV appears to increase with abnormal cytologic findings to 33% recovery in severe dysplasia or carcinoma in situ. |
| Databáze: | OpenAIRE |
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