Lewis Acid Mediated Vinylogous Additions of Enol Nucleophiles into an α,β-Unsaturated Platinum Carbene
| Autor: | Tarik J. Ozumerzifon, Paul Allegretti, Eric M. Ferreira, Khoi Huynh |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Annulation
Indoles chemistry.chemical_element 010402 general chemistry 01 natural sciences Biochemistry Article Catalysis chemistry.chemical_compound Nucleophile Organic chemistry Lewis acids and bases Physical and Theoretical Chemistry Benzofurans Lewis Acids Platinum Indole test Molecular Structure 010405 organic chemistry Organic Chemistry Enol 0104 chemical sciences chemistry Methane Carbene |
| Zdroj: | Organic Letters. 18:64-67 |
| ISSN: | 1523-7052 1523-7060 |
| DOI: | 10.1021/acs.orglett.5b03246 |
| Popis: | A variety of substituted indoles and benzofurans are accessed via a platinum catalyzed annulation and vinylogous addition of enol nucleophiles. Several β-dicarbonyl compounds participate in the reaction, as do α-nitro and α-cyano carbonyl species. Subjecting the indole products to acidic conditions results in the formation of fused heterocycles. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|