Physician and Nurse Beliefs of Phase 1 Trials in Pediatric Oncology
| Autor: | Avi Madan-Swain, Julia M Adams, Margaux J Barnes, Molly A. Hensler, Joseph G. Pressey |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Referral Attitude of Health Personnel Nurses Phase (combat) Article Likert scale Nursing Neoplasms Oncology Service Hospital Physicians Surveys and Questionnaires medicine Pediatric oncology Humans Dosing Child Referral and Consultation Clinical Trials Phase I as Topic Oncology (nursing) business.industry Phase 1 trials Middle Aged Oncology nursing Oncology Child Preschool Family medicine Female Perception business |
| Zdroj: | Cancer Nursing. 37:E48-E52 |
| ISSN: | 0162-220X |
| Popis: | BACKGROUND In order to improve the survival of children with cancer, novel therapies must be identified. Promising agents are tested in phase 1 trials in order to identify appropriate dosing and describe toxicity in children. The identification and referral of candidate patients for phase 1 trials rely heavily on medical providers who must balance their own perceptions of phase 1 trials with the desires and willingness of the patient and his/her family. OBJECTIVE The goal of the present study was to evaluate and compare physician and nurse perceptions regarding the beliefs, expectations, and perceived benefits of phase 1 clinical trials. METHODS A survey consisting of 21 questions was sent to 419 physicians and nurses practicing pediatric oncology at 30 different institutions. With the exception of 10 demographic questions, items were either rank ordered or rated on 5-point Likert scales. RESULTS Ninety-four physicians and 122 nurses completed the online survey. Physicians and nurses differed in their knowledge of the goals and medical effects of phase 1 clinical trials. CONCLUSIONS Physicians and nurses hold positive beliefs regarding phase 1 clinical trials and support their role in the treatment of children with cancer. Education is necessary to increase nurses' knowledge of the goals and outcomes. IMPLICATIONS FOR PRACTICE These findings suggest that continued education of nurses as well as physicians about the goals, execution, and monitoring of phase 1 therapy would be worthwhile. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|