Evaluation of Oxidative Stress and hsCRP in Polycystic Ovarian Syndrome in a Tertiary Care Hospital
| Autor: | N. Leela Menon, K. N. Subhakumari, R. Lakshman Lakshmi, V. S. Sheejamol, N. Unni C. Sumithra |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test endocrine system diseases business.industry Clinical Biochemistry nutritional and metabolic diseases Malondialdehyde medicine.disease_cause Prolactin Pathophysiology female genital diseases and pregnancy complications chemistry.chemical_compound Endocrinology Thyroid-stimulating hormone chemistry Internal medicine Endocrine system Medicine Original Article cardiovascular diseases business Lipid profile Oxidative stress Glycemic |
| Popis: | PCOS is a heterogeneous endocrine disorder with diverse clinical presentation. Oxidative stress plays a key role in the pathophysiology of this disease. Serumhigh sensitive C-reactive protein (hsCRP), a marker of chronic low grade inflammation, is indicative of future development of cardiovascular disease. Our aim is to evaluate the oxidant status and hsCRP levels in PCOS. The study involved 61 cases and 61 controls in the age group of 18–40 years diagnosed with PCOS. Erythrocyte malondialdehyde (MDA), superoxide dismutase (SOD), serum hsCRP, gonadotrophins, thyroid stimulating hormone, prolactin, glycemic status and lipid profile were estimated. Erythrocyte MDA (p |
| Databáze: | OpenAIRE |
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