Viral aetiology of lower respiratory tract infection in young Malaysian children
| Autor: | P. W. K. Chan, P. S. Hooi, A. Y. T. Goh, K. B. Chua, N. S. Kharullah |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Male
medicine.medical_specialty viruses Pneumonia Viral Virus Internal medicine Lower respiratory tract infection Humans Medicine Retrospective Studies Croup business.industry Viral culture Respiratory disease Infant Newborn Malaysia Infant medicine.disease Pneumonia Bronchiolitis Pediatrics Perinatology and Child Health Immunology Female Viral disease business |
| Zdroj: | Journal of Paediatrics and Child Health. 35:287-290 |
| ISSN: | 1440-1754 1034-4810 |
| DOI: | 10.1046/j.1440-1754.1999.00359.x |
| Popis: | Objective: To study the viral aetiology of lower respiratory tract infection (LRTI) in young Malaysian children. Methodology: A retrospective review was performed of LRTI patients aged less than 24 months who were admitted to the University Malaya Medical Centre between 1982 and 1997. Respiratory viruses in their nasopharyngeal secretion were identified by indirect immunofluorescence, viral culture, or both. Results: A total of 5691 children were included in the study. The mean age was 8.6 ± 6.6 months and the M:F ratio was 1.6:1. The most common diagnosis was pneumonia (52%) followed by bronchiolitis (45%) and croup (2%). Positive viral isolation rate was 22.0%. Respiratory syncytial virus (RSV) was the commonest virus isolated (84%), followed by parainfluenza virus (8%), influenza virus (6%) and adenovirus (2%). Patients with positive virus isolation were younger (7.8 ± 6.2 vs 8.7 ± 6.7 months, P = 0.0001) and were more likely to have bronchiolitis. Conclusion: Young Malaysian children admitted with LRTI had a 22% viral isolation rate and RSV was the commonest virus isolated. |
| Databáze: | OpenAIRE |
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