Use of Fibrin Glue as a Hemostatic in Endoscopic Sinus Surgery
Autor: | Ephraim Eviatar, Nathan Shlamkovich, Michael Vaiman, Samuel Segal |
---|---|
Rok vydání: | 2005 |
Předmět: |
Adult
Male medicine.medical_specialty Adolescent medicine.medical_treatment Turbinectomy Blood Loss Surgical Fibrin Tissue Adhesive Postoperative Hemorrhage Hemostatics law.invention 03 medical and health sciences Sleep Apnea Syndromes 0302 clinical medicine Double-Blind Method Randomized controlled trial law Outcome Assessment Health Care otorhinolaryngologic diseases medicine Humans Tampons Surgical Prospective Studies Sinusitis 030223 otorhinolaryngology Fibrin glue Prospective cohort study Pain Postoperative rhinorrhea medicine.diagnostic_test business.industry Endoscopy General Medicine Middle Aged Surgery Nasal Mucosa Paranasal sinuses medicine.anatomical_structure Otorhinolaryngology Tears 030220 oncology & carcinogenesis Anesthesia Submucous Resection Female medicine.symptom business |
Zdroj: | Annals of Otology, Rhinology & Laryngology. 114:237-241 |
ISSN: | 1943-572X 0003-4894 |
Popis: | Endoscopic sinus surgery (ESS), especially when combined with turbinectomy and/or with submucous resection of the septum, may involve postoperative bleeding that might end with nasal packing. Nasal packing causes pain, rhinorrhea, and inconvenience and may not stop the postoperative bleeding. The aim of our study was to compare the hemostatic properties of the second-generation surgical sealant Quixil (Crosseal) with those of nasal packing in ESS. We performed a prospective randomized trial in 64 consecutive patients who underwent ESS and presented excessive intraoperative and/or postoperative bleeding. They were allocated by the sealed-envelope method into two groups. A routine ESS procedure was ended with Merocel nasal packing in group 1, and with aerosol application of Quixil sealant at the operative site in group 2. The hemostatic effects were evaluated objectively in the clinic by anterior rhinoscopy and endoscopy and assessed subjectively by the patients at follow-up visits. In group 1, various types of postoperative bleeding occurred in 25% of patients. In group 2 there was no postoperative bleeding, except for 1 case of late hemorrhage (3.12%). Drainage and ventilation of the paranasal sinuses were not impaired. There were no allergic reactions to the glue. We conclude that aerosol application of fibrin glue can be readily performed in ESS, requires no special treatment (antibiotics), and appears to have an adequate hemostatic effect. The use of this second-generation glue in ESS appears to stop nasal bleeding well and to be relatively safe and convenient. |
Databáze: | OpenAIRE |
Externí odkaz: |