Clinical characteristics of coronavirus disease 2019 in Gansu province, China
| Autor: | Xun Li, Qin Yu, Hongmei Yue, Lihui Ding, Feng Tao, Xue Bai, Xiaoya Wang, Weiying Liu, Ning Kang, Jiayuan Pu, Xiaolong Qi, Long Li, Jitao Wang, Xiaoguo Li, Wenqiang Lu, Dan Xu, Jian-Ming Hu |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty China Adolescent medicine.medical_treatment Pneumonia Viral 030204 cardiovascular system & hematology medicine.disease_cause Asymptomatic 03 medical and health sciences Betacoronavirus Young Adult 0302 clinical medicine Interquartile range Internal medicine Epidemiology Medicine Humans Child Pandemics Coronavirus Aged Retrospective Studies Advanced and Specialized Nursing Mechanical ventilation Aged 80 and over business.industry SARS-CoV-2 COVID-19 Infant Retrospective cohort study Length of Stay Middle Aged medicine.disease Pneumonia Anesthesiology and Pain Medicine Treatment Outcome 030220 oncology & carcinogenesis Child Preschool Cohort Female medicine.symptom business Coronavirus Infections |
| Zdroj: | Annals of palliative medicine. 9(4) |
| ISSN: | 2224-5839 |
| Popis: | BACKGROUND: The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has outbreak in the world. Little is known about the clinical characteristics of patients with SARS-CoV-2 infection in the high-altitude region of China. We reported the clinical characteristics of patients with coronavirus disease 2019 (COVID-19) in Gansu province, China. METHODS: In this retrospective study, patients with laboratory-confirmed SARS-CoV-2 infection were consecutively enrolled from January 21, 2020 to February 11, 2020. The information on the epidemiological, clinical characteristics, laboratory tests, radiological features on admission, treatment and outcome were obtained with the final follow-up of March 13, 2020. On the basis of the median length of hospital stay, patients were further analyzed in two groups (long- vs. short-hospital stay). RESULTS: Of the 86 patients of COVID-19 in 11 cities of Gansu Province, the median hospital stay was 14.0 days (interquartile rang, 11.0-19.0 days). In the overall cohort, the median age was 41.0 years (interquartile rang, 31.0-54.3 years), and 48 (55.8%) patients were female. Forty (46.5%) had a history of exposure to epidemic regions, but none exposed to the Huanan seafood market in Wuhan. Common symptoms included fever (41, 47.7%), and cough (37, 43.0%). On admission, 30 (34.9%) and 58 (67.4%) patients had leukopenia and lymphopenia. According to chest CT scans, 53 (66.3%) of 80 patients showed bilateral pneumonia, and 19 (23.8%) of 80 patients showed unilateral pneumonia. Of the 15 asymptomatic cases, 10 (66.6%) cases were found CT findings of pneumonia. Besides, there were 65 (75.6%) patients with mild and moderate type of COVID-19. All 86 patients received antiviral and traditional Chinese medicine therapy, 53 (61.6%) received antibacterial therapy, and 3 (3.5%) patients received invasive ventilator mechanical ventilation. The proportion of patients received antibiotic treatment in long-hospital stay group was significantly higher than that in the short-hospital stay group (P=0.045). As of March 13, 2020, 84 (97.7%) patients were discharged, and two (2.3%) cases died. CONCLUSIONS: In the Gansu province cohort of 86 patients of COVID-19, most patients were with mild or moderate type, and most asymptomatic cases showed CT imaging findings of SARS-CoV-2 related pneumonia. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|