Barlerisides A and B, new potent superoxide scavenging phenolic glycosides from Barleria acanthoides

Autor:	Abdul Malik, Muhammad Iqbal Choudhary, Atia Tun Noor, Muhammad Imran Qadir, Aman Karim
Rok vydání:	2009
Předmět:	Pharmacology chemistry.chemical_classification Xanthine Oxidase Plant Extracts Stereochemistry Superoxide Anti-Inflammatory Agents Glycoside Free Radical Scavengers General Medicine Flavones chemistry.chemical_compound Enzyme Glucosides Phenols chemistry Biochemistry Superoxides Acanthaceae Drug Discovery Solvents Barleria acanthoides Glycosides Xanthine oxidase Scavenging
Zdroj:	Journal of Enzyme Inhibition and Medicinal Chemistry. 24:1332-1335
ISSN:	1475-6374 1475-6366
DOI:	10.3109/14756360902887046
Popis:	Barlerisides A (1) and B (2), new phenolic glycosides, have been isolated from the n-butanol soluble sub-fraction of Barleria acanthoides along with two known compounds acteoside (3) and p-hydroxycinnamic acid (4). Their structures have been assigned on the basis of spectral studies. Both 1 and 2 showed significant activity in the superoxide scavenging assay while weak inhibitory activity was observed against the enzyme xanthine oxidase.
Databáze:	OpenAIRE
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