Health-related quality of life among women with breast cancer - a population-based study
| Autor: | Mats Lambe, Marie Høyer, Annika Lidin-Lindqvist, Birgitta Johansson, Karin Nordin, Claudia Lampic, Johan Ahlgren, Leif Bergkvist |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Pediatrics medicine.medical_specialty Multivariate analysis Time Factors Population MEDLINE Breast Neoplasms Social support Breast cancer Quality of life Surveys and Questionnaires Medicine Humans Radiology Nuclear Medicine and imaging education Aged Aged 80 and over Sweden education.field_of_study business.industry Social Support Hematology General Medicine Middle Aged medicine.disease humanities Oncology Socioeconomic Factors Multivariate Analysis Physical therapy Disease Progression Quality of Life Normative Anxiety Female medicine.symptom business |
| Zdroj: | Acta oncologica (Stockholm, Sweden). 50(7) |
| ISSN: | 1651-226X |
| Popis: | High incidence rates of breast cancer emphasize the importance of increased knowledge about the health-related quality of life (HRQoL) in this patient group. The aim of the present study was to describe and compare HRQoL among breast cancer patients shortly after diagnosis with normative data from the general population, and to investigate how clinical, demographic, and socio-economic factors and social support are associated with HRQoL.Participants were identified in a population-based Breast Cancer Quality Register in central Sweden. Of 1573 women newly diagnosed with breast cancer during a one-year period (2007-2008), 69% (n = 1086) completed a questionnaire including the EORTC QLQ-C30, BR23 and the HADS.Compared to age-adjusted normative data, breast cancer patients (mean age 62 years, range 25-94), especially younger women (50 years), experienced clinically meaningful poorer HRQoL. Clinically significant levels of anxiety and depressive symptoms were found among 14% and 6% of the patients, respectively. Factors associated with more problems/symptoms among study participants included chemotherapy, lack of social support, sick leave and a poor financial situation. Adding socio-economic factors diminished the association between age and HRQoL (p0.05).Recently diagnosed breast cancer patients reported poorer HRQoL in several dimensions compared to normative data. In addition to clinical and demographic factors, an unfavorable socio-economic standing was associated with more problems/symptoms. The present findings emphasize the importance of taking a variety of factors into account when assessing HRQoL in the clinical setting. |
| Databáze: | OpenAIRE |
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