Cardiac magnetic resonance imaging characterizes stenosis, perfusion, and fibrosis preoperatively and postoperatively in children with anomalous coronary arteries

Autor: Julie A. Brothers, Timothy S. Kim, Mark A. Fogel, Kevin K. Whitehead, Tonia M. Morrison, Stephen M. Paridon, Matthew A. Harris
Rok vydání: 2016
Předmět:
Male
Pulmonary and Respiratory Medicine
medicine.medical_specialty
Adolescent
Coronary Vessel Anomalies
Magnetic Resonance Imaging
Cine

Angioscopy
030204 cardiovascular system & hematology
Ventricular Function
Left

Sudden cardiac death
Young Adult
03 medical and health sciences
0302 clinical medicine
Cardiac magnetic resonance imaging
Internal medicine
medicine.artery
Humans
Medicine
Prospective Studies
Cardiac Surgical Procedures
Child
Aorta
medicine.diagnostic_test
business.industry
Reproducibility of Results
Prognosis
medicine.disease
Coronary Vessels
Fibrosis
Coronary arteries
Ostium
medicine.anatomical_structure
030228 respiratory system
Child
Preschool

Anomalous aortic origin of a coronary artery
Cardiology
Female
Surgery
Radiology
Cardiology and Cardiovascular Medicine
business
Follow-Up Studies
Artery
Zdroj: The Journal of Thoracic and Cardiovascular Surgery. 152:205-210
ISSN: 0022-5223
DOI: 10.1016/j.jtcvs.2015.12.057
Popis: Using cardiac magnetic resonance imaging (MRI) with virtual angioscopy, we sought to evaluate coronary anatomy, myocardial injury, and left ventricular function in children with interarterial anomalous aortic origin of coronary artery before and after surgery.We prospectively enrolled children 5 to 19 years old with interarterial anomalous coronary artery. Cardiac MRI was performed with respiratory-navigated steady-state free-precession 3-dimensional data set acquisition. Virtual angioscopy was used to evaluate the coronary ostia directly. Surgery consisted of the modified unroofing procedure.We enrolled 9 subjects between February 2009 and May 2015. Subjects were male, with an average age at surgery of 14.1 years. Anomalous coronary was right in 7 patients (77%) and left in 2. In all subjects, the proximal anomalous coronary arose tangential to the aorta with an elliptical, slitlike ostium. Before the operation, the proximal coronary artery was significantly smaller proximally than distally (2 vs 3.1 mm; P .0001. After the operation, neo-orifices were round and patent in 7 subjects; however, 2 subjects still had narrowed neo-orifices. New postoperative MRI findings included flattened septal wall motion (N = 1), small region of midmyocardial partial-thickness scar (N = 1), and dyskinetic septal wall motion with mild aortic insufficiency (N = 1). Left ventricular function was normal both before and after surgery (P = .85).Cardiac MRI with virtual angioscopy is an important tool for evaluating anomalous coronary anatomy, myocardial function, and ischemia and should be considered for initial and postoperative assessment of children with anomalous coronary arteries.
Databáze: OpenAIRE