| Autor: |
J. Raymond DePaulo, Martin Alda, S H Juo, Philip B. Mitchell, Peter P. Zandi, Peter M. Visscher, Melvin G. McInnis, Johannes Schumacher, Michael Gill, Jenny Ekholm, Howard J. Edenberg, Stylianos E. Antonarakis, Nelson B. Freimer, Cathryn M. Lewis, Peter R. Schofield, Tatiana Foroud, Victor I. Reus, Jennifer A. Donald, Henrik Ewald, Takeo Yoshikawa, Conrad T. Gilliam, Rolf Adolfsson, Alison Goate, Theodore Reich, William Byerley, Elliot S. Gershon, Andrew McQuillin, Jouko Lönnqvist, Phil Bennett, Hugh Gurling, Paul Grof, Francis J. McMahon, Christine Windemuth, Judith A. Badner, L. J. Adams, John P. Rice, Wolfgang Maier, Michael Escamilla, Gursharan Kalsi, John I. Nurnberger, Douglas F. Levinson, Douglas Blackwood, Gustavo Turecki, Virginia L. Willour, Uppala Radhakrishna, Miron Baron, Hermann Luebbert, Jianjun Liu, Stuart MacGregor, Lynn R. Goldin, Eric Shink, Walter J. Muir, Pedro León, Torben A Kruse, Wade H. Berrettini, Nicholas John Craddock, Jurgen Del-Favero, John R. Kelsoe, Hilary Coon, Julien Mendlewicz, Sevilla D. Detera-Wadleigh, Jean-Louis Blouin, Leena Peltonen, Nurten A. Akarsu, Marcella Rietschel, Jean Morissette, Markus M. Nöthen, Christine Van Broeckhoven, M. Anne Spence, Peter Propping, Sven Cichon, Ole Mors, Nicholas Barden, Renee F. Badenhop, Stephan Claes, L. Alison McInnes, Ricardo Segurado, Guy A. Rouleau |
| Přispěvatelé: |
Blouin, Jean-Louis, Antonarakis, Stylianos |
| Rok vydání: |
2003 |
| Předmět: |
|
| Zdroj: |
ResearcherID
American Journal of Human Genetics, Vol. 73, No 1 (2003) pp. 49-62 |
| ISSN: |
0002-9297 |
| DOI: |
10.1086/376547 |
| Popis: |
PUBLISHED
PMID: 12802785
Genome scans of bipolar disorder (BPD) have not produced consistent evidence for linkage. The rank-based genome scan meta-analysis (GSMA) method was applied to 18 BPD genome scan data sets in an effort to identify regions with significant support for linkage in the combined data. The two primary analyses considered available linkage data for ?very narrow? (i.e., BP-I and schizoaffective disorder?BP) and ?narrow? (i.e., adding BP-II disorder) disease models, with the ranks weighted for sample size. A ?broad? model (i.e., adding recurrent major depression) and unweighted analyses were also performed. No region achieved genomewide statistical significance by several simulation-based criteria. The most significant P values (
Higher Education Authority |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
