Tobacco-specific nitrosamines (TSNA) in heated tobacco product IQOS
| Autor: | Mary Palumbo, Richard J O'Connor, Noel J. Leigh, Maciej L. Goniewicz, Anthony M Marino |
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| Rok vydání: | 2018 |
| Předmět: |
non-cigarette tobacco products
030505 public health Health (social science) Chemistry Extramural Public Health Environmental and Occupational Health Nicotine 03 medical and health sciences 0302 clinical medicine 13. Climate action Research Letter Curing of tobacco medicine Tobacco-specific nitrosamines 030212 general & internal medicine Food science 0305 other medical science Tobacco product electronic nicotine delivery devices medicine.drug |
| Zdroj: | Tobacco Control |
| ISSN: | 1468-3318 0964-4563 |
| DOI: | 10.1136/tobaccocontrol-2018-054318 |
| Popis: | Heated tobacco products (HTP) have an electrical heating component, like e-cigarettes, that heats processed tobacco to 350°C releasing volatile components that often are not detectable in e-cigarettes.1 Although many combustion by-products may be eliminated in HTP devices, nitrosamines are generated in the process of tobacco curing rather than during combustion, and may be transferred from the HTP into the aerosol that it generates.2–4 We hypothesised that HTP may be a significant source of tobacco-specific nitrosamines (TSNA). This pilot study determined TSNA yields in aerosol emitted from HTP in comparison to the electronic and tobacco cigarettes. HTP (IQOS; Amber, tobacco flavour), e-cigarettes (MarkTen; 3.5% nicotine, tobacco flavoured) and tobacco cigarettes (Marlboro Red 100) were tested using a Borgwaldt LX-1 smoking machine following the Health Canada Intense protocol (55 mL puff volume, 2 s duration, 30 s interval). Using this puffing protocol, we generated aerosol from a single HTP HeatStick (12 puffs), single tobacco cigarette (8 puffs) and from e-cigarette (55 puffs). We used different number of puffs for … |
| Databáze: | OpenAIRE |
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