Guanylin family

Autor: Shinya Yuge
Rok vydání: 2021
Předmět:
Popis: Guanylin (GN) and uroguanylin (UGN) peptides were first discovered as ligands of the guanylyl/guanylate cyclase C receptor (GC-C) in the rat in 1992 and in the opossum in 1993, respectively. The discoveries were brought about on the basis of the anticipation of the existence of endogenous ligand(s) that mimic structurally enterotoxigenic E. coli heat-stable enterotoxin (ST), a previously-known exogenous ligand of GC-C1.
Databáze: OpenAIRE