Coronal Sections of Larynges from Radiationtherapy Failures: A Clinical‐Pathologic Study
| Autor: | James H. Brandenburg, Terrence W. Frank, Kenneth G. Condon |
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| Rok vydání: | 1986 |
| Předmět: |
Glottis
medicine.medical_specialty Laryngeal Cartilages Laryngeal Cancers business.industry medicine.medical_treatment Cartilage Cancer Laryngectomy medicine.disease Cricoid Cartilage Radiation therapy medicine.anatomical_structure Otorhinolaryngology Coronal plane medicine Humans Neoplasm Invasiveness Surgery Radiology Larynx Neoplasm Recurrence Local business Laryngeal Neoplasms Neoplasm Staging |
| Zdroj: | Otolaryngology–Head and Neck Surgery. 95:213-218 |
| ISSN: | 1097-6817 0194-5998 |
| DOI: | 10.1177/019459988609500215 |
| Popis: | Serial coronal sections of 89 wide-field laryngectomies were examined. Twenty were specimens obtained from laryngectomies to treat patients for whom primary radiation therapy failed to cure early laryngeal cancer. These specimens were compared to 69 specimens from laryngectomies for T3, and T4, laryngeal cancers. The irradiation-failure group showed a significantly greater invasion of cartilage and extension into subglottic areas. The extension of tumors along blood vessels and mucous glands appeared to contribute to the spread of tumors in the irradiation-failure group. These findings have implications for the surgical management of irradiation failures in the treatment of laryngeal cancers. |
| Databáze: | OpenAIRE |
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