Optoacoustic imaging of the breast: correlation with histopathology and histopathologic biomarkers
Autor: | Ritse M. Mann, Philip T. Lavin, Ruud M. Pijnappel, Jeroen Veltman, Gisela L.G. Menezes, Bob H. C. Bisschops, Carla Meeuwis, Marc J. van de Vijver |
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Přispěvatelé: | Multi-Modality Medical Imaging |
Rok vydání: | 2019 |
Předmět: |
Adult
Oncology medicine.medical_specialty education UT-Hybrid-D Luma Molecular imaging Optoacoustic technologies 030218 nuclear medicine & medical imaging Diagnosis Differential Photoacoustic Techniques Correlation 03 medical and health sciences 0302 clinical medicine Breast cancer Internal medicine Biomarkers Tumor Journal Article medicine Humans Radiology Nuclear Medicine and imaging Breast Aged Retrospective Studies Neuroradiology Aged 80 and over business.industry General Medicine Middle Aged medicine.disease Women's cancers Radboud Institute for Health Sciences [Radboudumc 17] Radiology Nuclear Medicine and imaging 030220 oncology & carcinogenesis Female Histopathology Ultrasonography Mammary Radiology Breast neoplasms business Optoacoustic imaging |
Zdroj: | European Radiology, 29(12), 6728. Springer Verlag European Radiology European Radiology, 29, 12, pp. 6728-6740 European Radiology, 29, 6728-6740 European radiology, 29(12), 6728-6740. Springer |
ISSN: | 1432-1084 0938-7994 |
Popis: | Aim This study was conducted in order to investigate the role of gray-scale ultrasound (US) and optoacoustic imaging combined with gray-scale ultrasound (OA/US) to better differentiate between breast cancer molecular subtypes. Materials and methods All 67 malignant masses included in the Maestro trial were retrospectively reviewed to compare US and OA/US feature scores and histopathological findings. Kruskal–Wallis tests were used to analyze the relationship between US and OA/US features and molecular subtypes of breast cancer. If a significant relationship was found, additional Wilcoxon–Mann–Whitney tests were used to identify the differences between molecular subtype groups. Results US sound transmission helped to differentiate between LUMA and LUMB, LUMB and TNBC, and LUMB and all other molecular subtypes combined (p values |
Databáze: | OpenAIRE |
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