Optoacoustic imaging of the breast: correlation with histopathology and histopathologic biomarkers

Autor: Ritse M. Mann, Philip T. Lavin, Ruud M. Pijnappel, Jeroen Veltman, Gisela L.G. Menezes, Bob H. C. Bisschops, Carla Meeuwis, Marc J. van de Vijver
Přispěvatelé: Multi-Modality Medical Imaging
Rok vydání: 2019
Předmět:
Zdroj: European Radiology, 29(12), 6728. Springer Verlag
European Radiology
European Radiology, 29, 12, pp. 6728-6740
European Radiology, 29, 6728-6740
European radiology, 29(12), 6728-6740. Springer
ISSN: 1432-1084
0938-7994
Popis: Aim This study was conducted in order to investigate the role of gray-scale ultrasound (US) and optoacoustic imaging combined with gray-scale ultrasound (OA/US) to better differentiate between breast cancer molecular subtypes. Materials and methods All 67 malignant masses included in the Maestro trial were retrospectively reviewed to compare US and OA/US feature scores and histopathological findings. Kruskal–Wallis tests were used to analyze the relationship between US and OA/US features and molecular subtypes of breast cancer. If a significant relationship was found, additional Wilcoxon–Mann–Whitney tests were used to identify the differences between molecular subtype groups. Results US sound transmission helped to differentiate between LUMA and LUMB, LUMB and TNBC, and LUMB and all other molecular subtypes combined (p values
Databáze: OpenAIRE