A Heritable Connective Tissue Disease of Dogs and Mink Resembling Ehlers-Danlos Syndrome of Man I. Skin Tensile Strength Properties
| Autor: | Gerald A. Hegreberg, George A. Padgett, R L Ott, James B. Henson |
|---|---|
| Rok vydání: | 1970 |
| Předmět: |
Pathology
medicine.medical_specialty Connective tissue Dermatology Skin Diseases Biochemistry Diagnosis Differential Physical Phenomena Dogs Skin fragility biology.animal Ultimate tensile strength medicine Animals Humans Dog Diseases Mink Pathology Veterinary Molecular Biology Skin biology integumentary system business.industry Physics Anatomy Cell Biology medicine.disease Connective tissue disease Joint hyperextensibility medicine.anatomical_structure Connective Tissue Ehlers–Danlos syndrome Skin laxity Ehlers-Danlos Syndrome business |
| Zdroj: | Journal of Investigative Dermatology. 54(5):377-380 |
| ISSN: | 0022-202X |
| DOI: | 10.1111/1523-1747.ep12259079 |
| Popis: | Clinical changes observed in a heritable connective tissue disease of dogs and mink include fragility, hyperextensibility, and laxity of the skin. Skin fragility is the most severe and consistent change noted in the affected dogs and mink. Tensile strength of the skin was reduced to one-twenty-seventh that of normal in affected dogs and one- thirteenth that of normal in affected mink. The syndrome in dogs and mink is proposed as a homolog of the Ehlers-Danlos syndrome of man, a rare heritable connective tissue disease, which is clinically characterized by skin fragility, skin and joint hyperextensibility and skin laxity. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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