Comparison of numerical and standard sarnat grading using the NICHD and SIBEN methods
| Autor: | Terrie E. Inder, Chelsea Munster, Hoda El-Shibiny, Brian H. Walsh, Mohamed El-Dib, Edward Yang |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Cerebral injury Receiver operating characteristic Neonatal encephalopathy business.industry Infant Newborn Infant National Institute of Child Health and Human Development (U.S.) Obstetrics and Gynecology medicine.disease Infant Newborn Diseases United States ROC Curve Brain Injuries Pediatrics Perinatology and Child Health medicine Humans Radiology business Grading (tumors) Kappa |
| Zdroj: | Journal of Perinatology. 42:328-334 |
| ISSN: | 1476-5543 0743-8346 |
| Popis: | Objective The NICHD and SIBEN assessments are adapted from the Sarnat grade, and used to determine severity of neonatal encephalopathy (NE). We compare NICHD and SIBEN methods, and their ability to define a minimum threshold associated with significant cerebral injury. Study design Between 2016 and 2019, 145 infants with NE (77-mild; 65-moderate; 3-severe) were included. NICHD and SIBEN grade and numerical scores were assigned. Kappa scores described agreement between methods, and ROC curves their ability to predict MR injury. Results Good agreement existed between grading systems (K = 0.86). SIBEN defined more infants as moderate, and less as mild, than NICHD (p Conclusion Despite good agreement between methods, SIBEN defines more infants as moderate NE. Both numerical scores were superior to standard grade, and comparable to each other, in defining a minimum threshold for cerebral injury. Further assessment contrasting their predictive ability for long-term outcome is required. |
| Databáze: | OpenAIRE |
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