Supplemental Figure 1 Schematics of the tetracycline inducible-FIP1C-MTB and inducible knock-out FIP1C mouse models from Rab11-FIP1C Is a Critical Negative Regulator in ErbB2-Mediated Mammary Tumor Progression

Autor: William J. Muller, Jim C. Norman, Douglas Strathdee, Lewis Chodosh, Morag Park, Gordon B. Mills, Michael Hallett, Shirley Campbell, Julie M. Livingstone, Shreya Mitra, Laura Jones, Virginie Sanguin-Gendreau, Cynthia Lavoie, Julie-Émilie Huot-Marchand, Jason Turpin, Louise Mitchell, Pierre-Luc Boulay
Rok vydání: 2023
DOI: 10.1158/0008-5472.22412007.v1
Popis: This Supplemental Figure 1 describes engineering of FIP1C inducible mouse model and condition knockout. Moreover, Supplemental Figure 1 provides data related to the elucidation of the physiological role of FIP1C during mamamry gland outgrowth as a supplement of Figure 1. Overall,the modulation of FIP1C levels in mammary gland does not affect normal mammary gland development.
Databáze: OpenAIRE