Integration and Bio-Functionalization of Vertically Aligned Carbon Nanotube Forests on High Frequency AlN Gravimetric Sensors
| Autor: | Diego Megias, Jimena Olivares, José Miguel Escolano, Enrique Iborra, Teona Mirea, Bruno Marco, Marta Clement |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Streptavidin
0209 industrial biotechnology Materials science Nanotechnology lcsh:A 02 engineering and technology Carbon nanotube Conjugated system 01 natural sciences Capacitance law.invention chemistry.chemical_compound carbon nanotube forest integration 020901 industrial engineering & automation law bio-functionalization chemistry.chemical_classification Telecomunicaciones 010401 analytical chemistry Polymer 0104 chemical sciences gravimetric bio-sensors chemistry AlN electroacoustic resonators Surface modification Gravimetric analysis lcsh:General Works Biosensor |
| Zdroj: | Proceedings, Vol 1, Iss 4, p 537 (2017) Proceedings of Eurosensors 2017 | Eurosensors 2017 | 03/09/2017-6/09/2017 | Paris, France Archivo Digital UPM Universidad Politécnica de Madrid |
| ISSN: | 2504-3900 |
| Popis: | In this work, we grow different types of carbon nanotube (CNT) forests directly on AlN-based electroacoustic biosensors and study their functionalization efficiency. CNTs are used to increase the effective surface area of the sensor, pursuing a better sensitivity, without increasing the sensor capacitance. Here we use a general method for CNT bio-functionalization with specific receptors for targeted species. First, we make them hydrophilic. Next, we cover them with alternating polymers. Finally, we incubate their surface in an N-hydroxysuccinimide biotin solution. To study the functionalization homogeneity along the CNT length, Streptavidin conjugated with fluorescein isothiocyanate is used as the targeted species for confocal fluorescence microscopy characterization. |
| Databáze: | OpenAIRE |
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