Heterocyclic compounds as a magic bullet for diabetes mellitus: a review

Autor: Umme Farwa, Muhammad Asam Raza
Rok vydání: 2022
Předmět:
Zdroj: RSC Advances. 12:22951-22973
ISSN: 2046-2069
DOI: 10.1039/d2ra02697j
Popis: Diabetes mellitus (DM) is a major metabolic disorder due to hyperglycemia, which is increasing all over the world. From the last two decades, the use of synthetic agents has risen due to their major involvement in curing of chronic diseases including DM. The core skeleton of drugs has been studied such as thiazolidinone, azole, chalcone, pyrrole and pyrimidine along with their derivatives. Diabetics assays have been performed in consideration of different enzymes such as α-glycosidase, α-amylase, and α-galactosidase against acarbose standard drug. The studied moieties were depicted in both models
Databáze: OpenAIRE