Clinical significance of arterial stiffness as a factor for hospitalization of heart failure with preserved left ventricular ejection fraction: a retrospective matched case-control study
| Autor: | Arifumi Kikuchi, Yusuke Ito, Masahiro Ishikawa, Shiro Ishihara, Yuji Maruyama, Satoru Ohkuma, Noriyuki Kobayashi, Tatsuya Mitsuishi, Koji Takagi, Toshiya Omote, Wataru Shimizu, Shunichi Nakamura, Tsuyoshi Nohara, Naoto Takahashi, Hajime Imura, Naoki Sato, Hayano Iha, Shota Shigihara, Nakama Kenji, Hideo Tokuyama, Michiko Sone, Atsushi Ishizuka, Eisei Yamamoto, Kenichi Amitani |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty 030204 cardiovascular system & hematology Coronary artery disease 03 medical and health sciences 0302 clinical medicine Vascular Stiffness Risk Factors Internal medicine medicine Humans 030212 general & internal medicine Risk factor Aged Retrospective Studies Aged 80 and over Heart Failure Ejection fraction business.industry Case-control study Middle Aged medicine.disease Hospitalization Heart failure Case-Control Studies Cardiology Arterial stiffness Female Cardiology and Cardiovascular Medicine business Heart failure with preserved ejection fraction Dyslipidemia |
| Zdroj: | Journal of cardiology. 76(2) |
| ISSN: | 1876-4738 |
| Popis: | Previous studies have been conducted to identify characteristics of patients with heart failure with preserved ejection fraction (HFpEF), but the risk factors of HFpEF remain unclear. We investigated the associations between arterial stiffness and the risk of hospitalization for HFpEF patients.For the case group, we enrolled patients with preserved EF who had been hospitalized for HF from April 2013 to March 2015 and examined the cardio-ankle vascular index (CAVI). For the control group, we enrolled outpatients with preserved EF and with hypertension, diabetes mellitus, dyslipidemia, and/or coronary artery disease but who did not present with HF symptoms and had never been diagnosed or treated for HF during the same period. The control group matched with the case group for age and sex. The association between hospitalized HFpEF and clinical variables was analyzed using conditional logistic regression models.The CAVI value was significantly higher in patients with hospitalized HFpEF compared with patients with the control [10.4 (9.8-11.0) vs. 9.2 (8.1-10.0), p0.001). On the multivariate conditional logistic regression analysis, high CAVI (OR 6.76, 95% CI 2.28-20.10, p0.001) and anemia (OR 3.91, 95% CI 1.47-10.40, p = 0.006) were independently associated with hospitalization of HFpEF patients.The present study has demonstrated that the high value of CAVI was independently associated with the hospitalization of HFpEF patients. |
| Databáze: | OpenAIRE |
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