Higher recovery rate of microorganisms from cerebrospinal fluid samples by the BACTEC culture system in comparison with agar culture
| Autor: | Carlo Chezzi, Silvia Covan, Flora De Conto, Maria Cristina Medici, Monica Martinelli, Sandra Larini, Federica Motta, Adriana Calderaro, Sara Montecchini, Maria Cristina Arcangeletti |
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| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Adult Male food.ingredient Time Factors Adolescent Microorganism 030106 microbiology Sensitivity and Specificity Microbiology Meningitis Bacterial 03 medical and health sciences Young Adult 0302 clinical medicine Cerebrospinal fluid food Recovery rate medicine Agar Humans Blood culture 030212 general & internal medicine Child Aged Cerebrospinal Fluid Aged 80 and over Bacteriological Techniques Time to detection medicine.diagnostic_test business.industry Infant Newborn Infant General Medicine Middle Aged Combined approach Infectious Diseases Child Preschool Female Detection rate business |
| Zdroj: | Diagnostic microbiology and infectious disease. 84(4) |
| ISSN: | 1879-0070 |
| Popis: | The aim of this study was to assess the diagnostic value of the BACTEC FX blood culture (BC) system as compared to the agar culture (AC) of cerebrospinal fluid samples (CSF), evaluating the recovery rate and the time to detection of microorganisms in a 3.5-year period. From December 2011 to May 2015, 1326 CSF samples (694 patients) were submitted to both AC and BC. Among the 150 positive samples (96 patients), 165 microorganisms were detected: 81 by both the protocols, 77 by BC alone, and 7 by AC alone, demonstrating a higher detection rate of BC (95.8%) than AC (53.3%). Although BC presents some disadvantages, it is able to improve the yield of clinically significant microorganisms, and it could potentially reduce the reporting time as compared to AC. The results obtained highlighted the necessity of a combined approach for the successful detection of central nervous system microbial infections. |
| Databáze: | OpenAIRE |
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