How does the addition of shape distinct gold nanoparticles influence on the conformational transition of poly(N-isopropylacrylamide)?
| Autor: | Pannuru Venkatesu, Ritu Yadav, Payal Narang, Sumit Kumar |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Materials science
Acrylic Resins Nanoparticle Metal Nanoparticles 02 engineering and technology 010402 general chemistry 01 natural sciences Lower critical solution temperature Nanomaterials Biomaterials chemistry.chemical_compound Colloid and Surface Chemistry Differential scanning calorimetry Dynamic light scattering Humans Temperature 021001 nanoscience & nanotechnology 0104 chemical sciences Surfaces Coatings and Films Electronic Optical and Magnetic Materials chemistry Chemical engineering Colloidal gold Poly(N-isopropylacrylamide) Nanorod Gold 0210 nano-technology |
| Zdroj: | Journal of colloid and interface science. 582 |
| ISSN: | 1095-7103 |
| Popis: | Hypothesis The subject of nanomaterials has created immense interest and expectations in the field of science and nanotechnology. Plentiful aspects proposed by gold nanoparticles (AuNPs) and their capability to affect macromolecular transition is the main driving force to execute the current study. A thermo-responsive polymer poly(N-isopropylacrylamide) (pNIPAM) is studied in presence of nanoparticles, particularly gold nanorods and nanospheres to elucidate completely the effect of their shape, surface area and structural morphology on the conformation of pNIPAM. Experiments In this respect, several biophysical techniques such as fluorescence spectroscopy, dynamic light scattering (DLS), Fourier transform infrared spectroscopy (FTIR) and differential scanning calorimetry (DSC) are utilized to examine the interaction of Au nanospheres/nanorods with pNIPAM. For a better understanding of Au nanoparticles morphology, transmission electron microscopy (TEM) is also employed. Findings Introducing gold nanoparticles with the polymeric solution promotes the polymer to stay in the coil conformation at a higher temperature than the LCST of aqueous pNIPAM. A shift of 2 and 25.5 °C in the LCST of pNIPAM is observed along with Au nanospheres and nanorods, respectively. The current study provides a better impact in the field of biomedical science specifically drug delivery and tissue engineering as the LCST approaches human body temperature. |
| Databáze: | OpenAIRE |
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