Magnetic Resonance Imaging and Computed Tomography for the Noninvasive Assessment of Arterial Aging: A Review by the VascAgeNet COST Action
| Autor: | Elisabetta Bianchini, Mai Tone Lønnebakken, Peter Wohlfahrt, Senol Piskin, Dimitrios Terentes‐Printzios, Jordi Alastruey, Andrea Guala |
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| Přispěvatelé: | Institut Català de la Salut, [Bianchini E] Institute of Clinical Physiology, CNR, Pisa, Italy. [Lønnebakken MT] Department of Clinical Science, University of Bergen, Bergen, Norway. Department of Heart Disease, Haukeland University Hospital, Bergen, Norway. [Wohlfahrt P] Department of Preventive Cardiology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic. Centre for Cardiovascular Prevention, Charles University Medical School I and Thomayer Hospital, Prague, Czech Republic. Department of Medicine II, Charles University in Prague, First Faculty of Medicine, Prague, Czech Republic. [Piskin S] Department of Mechanical Engineering, Faculty of Engineering and Natural Sciences, Istinye University, Istanbul, Turkey. Modeling, Simulation and Extended Reality Laboratory, Istinye University, Istanbul, Turkey. [Terentes-Printzios D] Department of Cardiology, Hippokration Hospital, Athens Medical School, National and Kapodistrian University of Athens, Greece. [Alastruey J] School of Biomedical Engineering and Imaging Sciences, King’s College London, London, UK. [Guala A] Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. CIBER-CV, Instituto de Salud Carlos III, Madrid, Spain, Vall d'Hebron Barcelona Hospital Campus |
| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: |
Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Image Interpretation
Computer-Assisted::Tomography X-Ray Computed [ANALYTICAL DIAGNOSTIC AND THERAPEUTIC TECHNIQUES AND EQUIPMENT] Artèries Tomografia Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Tomography::Magnetic Resonance Imaging [ANALYTICAL DIAGNOSTIC AND THERAPEUTIC TECHNIQUES AND EQUIPMENT] Marcadors bioquímics diagnóstico::técnicas y procedimientos diagnósticos::diagnóstico por imagen::interpretación de imágenes asistida por ordenador::tomografía computarizada por rayos X [TÉCNICAS Y EQUIPOS ANALÍTICOS DIAGNÓSTICOS Y TERAPÉUTICOS] Imatgeria per ressonància magnètica Cardiovascular System::Blood Vessels::Arteries [ANATOMY] diagnóstico::técnicas y procedimientos diagnósticos::diagnóstico por imagen::tomografía::imagen por resonancia magnética [TÉCNICAS Y EQUIPOS ANALÍTICOS DIAGNÓSTICOS Y TERAPÉUTICOS] Cardiology and Cardiovascular Medicine Biological Factors::Biomarkers [CHEMICALS AND DRUGS] factores biológicos::biomarcadores [COMPUESTOS QUÍMICOS Y DROGAS] sistema cardiovascular::vasos sanguíneos::arterias [ANATOMÍA] |
| Zdroj: | Scientia |
| Popis: | Aging; Aorta; Calcification Envelliment; Aorta; Calcificació Envejecimiento; Aorta; Calcificación Magnetic resonance imaging and computed tomography allow the characterization of arterial state and function with high confidence and thus play a key role in the understanding of arterial aging and its translation into the clinic. Decades of research into the development of innovative imaging sequences and image analysis techniques have led to the identification of a large number of potential biomarkers, some bringing improvement in basic science, others in clinical practice. Nonetheless, the complexity of some of these biomarkers and the image analysis techniques required for their computation hamper their widespread use. In this narrative review, current biomarkers related to aging of the aorta, their founding principles, the sequence, and postprocessing required, and their predictive values for cardiovascular events are summarized. For each biomarker a summary of reference values and reproducibility studies and limitations is provided. The present review, developed in the COST Action VascAgeNet, aims to guide clinicians and technical researchers in the critical understanding of the possibilities offered by these advanced imaging modalities for studying the state and function of the aorta, and their possible clinically relevant relationships with aging. This article is based upon work from COST Action CA18216 VascAgeNet, supported by COST (European Cooperation in Science and Technology, www.cost.eu). A. Guala has received funding from Spanish Ministry of Science, Innovation and Universities (IJC2018‐037349‐I) and from “la Caixa” Foundation (LCF/BQ/PR22/11920008). S. Piskin has received funding from the European Research Executive Agency, Marie‐Sklodowska Curie Actions‐Global Individual Fellowship (101038096), and from Istinye University, Scientific Research Projects project (2019B1). P. Wohlfahrt's work was supported by the Ministry of Health of the Czech Republic, grant no. NV 19‐09‐00125. J. Alastruey was supported by the British Heart Foundation under Grant PG/15/104/31913, the Wellcome Engineering and Physical Sciences Research Council Centre for Medical Engineering at King's College London under Grant WT 203148/Z/16/Z, and the UK Department of Health through the National Institute for Health Research Cardiovascular MedTech Co‐Operative at Guy's and St Thomas' National Health Service Foundation Trust under grant MIC‐2016‐019. |
| Databáze: | OpenAIRE |
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