Case-Control Analysis of the Impact of Anemia on Quality of Life in Patients with Cancer: A Qca Study Analysis
| Autor: | Gonzalo Garcia-Gonzalez, Eduardo Rios-Herranz, Leyre Chasco-Eguilaz, Macarena Real-Dominguez, Maria Isabel Asensio-Cruz, Ignacio Garcia-Escobar, Jose Maria Sanchez-Diaz, Iria Gallego-Gallego, Samira Marin-Romero, Maria Carmen Borrego-Delgado, Alfonso Revuelta-Rodriguez, Aitor Ballaz-Quincoces, Maria Carmen Areses, Jorge Lima-Alvarez, Lucia Marin-Barrera, Andres J Muñoz-Martin, Carmen Beato, Maria Barca-Hernando, Maria Angeles Moreno-Santos, Sergio Lopez-Ruz, Purificacion Estevez-Garcia, J.B. López-Sáez, Estefania Oncala-Sibajas, Remedios Otero-Candelera, Teresa Elias-Hernandez, Carme Font, Victor Rivas-Jimenez, Luis Jara-Palomares |
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| Přispěvatelé: | Medicina |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Cancer Research
medicine.medical_specialty Anemia Mean difference Article 03 medical and health sciences 0302 clinical medicine Quality of life Internal medicine medicine Global health In patient 030212 general & internal medicine Study analysis RC254-282 anaemia business.industry Neoplasms. Tumors. Oncology. Including cancer and carcinogens Cancer medicine.disease humanities Oncology quality of life 030220 oncology & carcinogenesis Case control analysis business neoplasm |
| Zdroj: | Cancers 2021, 13(11), 2517 Cancers Volume 13 Issue 11 RODIN. Repositorio de Objetos de Docencia e Investigación de la Universidad de Cádiz instname Cancers, Vol 13, Iss 2517, p 2517 (2021) |
| Popis: | Anemia is a common condition in cancer patients and is associated with a wide variety of symptoms that impair quality of life (QoL). However, exactly how anemia affects QoL in cancer patients is unclear because of the inconsistencies in its definition in previous reports. We aimed to examine the clinical impact of anemia on the QoL of cancer patients using specific questionnaires. We performed a post-hoc analysis of a multicenter, prospective, case-control study. We included patients with cancer with (cases) or without (controls) anemia. Participants completed the European Organization for Research and Treatment of Cancer Quality of Life questionnaire version 3.0 (EORTC QLQ-C30) and Euro QoL 5-dimension 3-level (EQ−5D−3L) questionnaire. Statistically significant and clinically relevant differences in the global health status were examined. From 2015 to 2018, 365 patients were included (90 cases and 275 controls). We found minimally important differences in global health status according to the EORTC QLQ-C30 questionnaire (case vs. controls: 45.6 vs. 58%, respectively mean difference: −12.4, p < 0.001). Regarding symptoms, cancer patients with anemia had more pronounced symptoms in six out of nine scales in comparison with those without anemia. In conclusion, cancer patients with anemia had a worse QoL both clinically and statistically. |
| Databáze: | OpenAIRE |
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