Cost-effectiveness of minimally invasive sacroiliac joint fusion
| Autor: | Daniel J. Cher, Melissa A. Frasco, David W. Polly, Renée J.G. Arnold |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Cost effectiveness Economics Econometrics and Finance (miscellaneous) sacroiliac joint arthrodesis law.invention spine surgery Sacroiliac joint dysfunction Randomized controlled trial law medicine sacroiliac joint disruptions sacroiliac joint dysfunction minimally invasive surgery health care economics and organizations Original Research Sacroiliac joint business.industry Health Policy Sacroiliitis cost-effectiveness analysis Cost-effectiveness analysis medicine.disease Confidence interval Surgery Clinical trial ClinicoEconomics and Outcomes Research medicine.anatomical_structure Physical therapy medicine.symptom business degenerative sacroiliitis |
| Zdroj: | ClinicoEconomics and Outcomes Research: CEOR |
| ISSN: | 1178-6981 |
| Popis: | Daniel J Cher,1 Melissa A Frasco,2 Renée JG Arnold,2,3 David W Polly4,5 1Clinical Affairs, SI-BONE, Inc., San Jose, CA, USA; 2Division of Health Economics and Outcomes Research, Quorum Consulting, Inc., San Francisco, CA, USA; 3Department of Preventive Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA; 4Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, MN, USA; 5Department of Neurosurgery, University of Minnesota, Minneapolis, MN, USA Background: Sacroiliac joint (SIJ) disorders are common in patients with chronic lower back pain. Minimally invasive surgical options have been shown to be effective for the treatment of chronic SIJ dysfunction. Objective: To determine the cost-effectiveness of minimally invasive SIJ fusion. Methods: Data from two prospective, multicenter, clinical trials were used to inform a Markov process cost-utility model to evaluate cumulative 5-year health quality and costs after minimally invasive SIJ fusion using triangular titanium implants or non-surgical treatment. The analysis was performed from a third-party perspective. The model specifically incorporated variation in resource utilization observed in the randomized trial. Multiple one-way and probabilistic sensitivity analyses were performed. Results: SIJ fusion was associated with a gain of approximately 0.74 quality-adjusted life years (QALYs) at a cost of US$13,313 per QALY gained. In multiple one-way sensitivity analyses all scenarios resulted in an incremental cost-effectiveness ratio (ICER) |
| Databáze: | OpenAIRE |
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