Evaluation of Lean Body Weight Equation by Dual-Energy X-Ray Absorptiometry Measures
| Autor: | Paige Fisher, Charlene Compher, Lauren M. Beckman, Joseph I. Boullata, Carrie P. Earthman |
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| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
Adult medicine.medical_specialty Pediatrics Adolescent Minnesota Gastric Bypass Medicine (miscellaneous) Body weight Body Mass Index 03 medical and health sciences Young Adult Absorptiometry Photon Weight loss Intestinal failure medicine Humans In patient Obesity Dual-energy X-ray absorptiometry Adiposity Aged 030109 nutrition & dietetics Nutrition and Dietetics medicine.diagnostic_test business.industry Body Weight Middle Aged Pennsylvania Surgery Lean body mass Body Composition Linear Models Female Single point medicine.symptom business Parenteral Nutrition Home Body mass index Follow-Up Studies |
| Zdroj: | JPEN. Journal of parenteral and enteral nutrition. 41(3) |
| ISSN: | 1941-2444 |
| Popis: | BACKGROUND When managing patients with disorders that require clinical intervention, a practical assessment of body habitus is valued. The Duffull-Green lean body weight (LBW) equation was derived and validated in adults across a wide body mass index (BMI) range. Whether this predictive equation will perform well in patients at BMI extremes or perform better than a widely used empiric "ideal" body weight (IBW) equation is unknown. MATERIALS AND METHODS Calculated LBW and calculated IBW were each compared with the dual-energy x-ray absorptiometry (DXA)-derived lean body mass (LBM) by simple linear regression. A mixed model was used to determine how well the LBW equation performed over time in patients with more than 1 DXA measurement. RESULTS At time 0, 32 patients were 18-67 years old, and all were obese (BMI: 36-65 kg/m2), while the remaining 7 had parenteral nutrition-dependent intestinal failure (BMI: 17-25 kg/m2). A subset of patients underwent bariatric surgery after time 0 (BMI at follow-up: 22-49 kg/m2). The LBW equation was a predictor of LBM ( R2 = 0.67, P < .0001), while the IBW equation was not ( R2 = 0.04, P = .25). The LBW equation remained a predictor of LBM over time ( P < .0001) without significant interaction by number of months since time 0. CONCLUSION The Duffull-Green LBW equation successfully predicted lean body mass in a patient population with a wide range of BMIs at both a single point in time and after considerable weight loss. In the clinical setting, an equation that performs well in various disease states and body sizes is advantageous. |
| Databáze: | OpenAIRE |
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