Cariogenic and oral health taxa in the oral cavity among children and adults: A scoping review
| Autor: | Betsy Foxman, Deesha Bhaumik, Divya Manikandan |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
medicine.medical_specialty Saliva Oral Health Dental Caries Oral health Oral cavity Dental plaque Article Streptococcus mutans RNA Ribosomal 16S Internal medicine medicine Humans Sample Type Child General Dentistry Mouth Human studies biology business.industry Cell Biology General Medicine Fusobacterium biology.organism_classification medicine.disease Otorhinolaryngology Oral Microbiome business |
| Zdroj: | Arch Oral Biol |
| ISSN: | 0003-9969 |
| Popis: | Objective To review published oral microbiome studies and create a comprehensive list of bacterial species found in saliva and dental plaque among healthy children and adults associated with presence of carious lesions and caries-free state (oral health). Design This review followed PRISMA‐ScR guidelines. We searched published studies querying PUBMED and EMBASE using the following keywords: (plaque OR saliva) AND caries AND (next generation sequencing OR checkerboard OR 16s rRNA or qPCR). Studies were limited to human studies published in English between January 1, 2010 and June 24, 2020 that included > 10 caries-active and > 10 caries-free participants, and assessed the entire bacterial community. Results Our search strategy identified 298 articles. After exclusion criteria, 22 articles remained; we considered 2 studies that examined saliva and plaque as separate studies, for a total of 24 studies. Species associated with caries or oral health varied widely among studies reviewed, with notable differences by age and biologic sample type. No bacterial species was associated with caries in all studies. Streptococcus mutans was found more frequently among those with caries (14/24 (58.3 %)) and Fusobacterium periodonticum was found more frequently among those that were caries-free (5/24 (20.8 %)). Conclusion No bacterial species was associated with caries or oral health across all studies supporting multiple pathways to cariogenesis. However, the variation may be due to sampling at different time points during caries development, varying methods of specimen sampling, storage, sequencing or analysis or differences in host factors such as age. |
| Databáze: | OpenAIRE |
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