Visual analysis of automated segmentation in the diagnosis of focal cortical dysplasias with magnetic resonance imaging
| Autor: | María de la Iglesia-Vayá, Facundo las Heras, Evelyng Faure, Claudio R. Pardo, Marcelo Galvez, Cecilia Okuma, Gonzalo M. Rojas, Jorge Cordovez, M. Magdalena Sepúlveda, José Molina-Mateo |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent FreeSurfer Automated segmentation Focal cortical dysplasia Young Adult 03 medical and health sciences Behavioral Neuroscience Mri image 0302 clinical medicine medicine Humans Brain segmentation Segmentation 030212 general & internal medicine FCD Negative studies Child Retrospective Studies Epilepsy medicine.diagnostic_test business.industry Brain Magnetic resonance imaging medicine.disease Magnetic Resonance Imaging Malformations of Cortical Development Neurology Dysplasia Child Preschool FISICA APLICADA Female Neurology (clinical) Radiology business Cortical thickening 030217 neurology & neurosurgery |
| Zdroj: | RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia instname |
| DOI: | 10.1016/j.yebeh.2019.106684 |
| Popis: | [EN] Focal cortical dysplasias (FCDs) are a frequent cause of epilepsy. It has been reported that up to 40% of them cannot be visualized with conventional magnetic resonance imaging (MRI). The main objective of this work was to evaluate by means of a retrospective descriptive observational study whether the automated brain segmentation is useful for detecting FCD. One hundred and fifty-five patients, who underwent surgery between the years 2009 and 2016, were reviewed. Twenty patients with FCD confirmed by histology and a preoperative segmentation study, with ages ranging from 3 to 43 years (14 men), were analyzed. Three expert neuroradiologists visually analyzed conventional and advancedMRI with automated segmentation. They were classified into positive and negative concerning visualization of FCD by consensus. Of the 20 patients evaluated with conventional MRI, 12 were positive for FCD.Of the negative studies for FCD with conventional MRI, 2 (25%) were positive when they were analyzed with automated segmentation. In 13 of the 20 patients (with positive segmentation for FCD), cortical thickening was observed in 5 (38.5%), while pseudo thickening was observed in the rest of patients (8, 61.5%) in the anatomical region of the brain corresponding to the dysplasia. This work demonstrated that automated brain segmentation helps to increase detection of FCDs that are unable to be visualized in conventional MRI images. |
| Databáze: | OpenAIRE |
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