The effectiveness of pedicle screw immersion in vancomycin and ceftriaxone solution for the prevention of postoperative spinal infection: A prospective comparative study
| Autor: | Nezih Ozkan, Feyza Karagoz Guzey, Cafer Korkut, Serkan Kitiş, Burak Eren |
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| Přispěvatelé: | Acibadem University Dspace, KİTİŞ, SERKAN |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
Antibiotics medicine.disease_cause Neurosurgical Procedures 0302 clinical medicine lcsh:Orthopedic surgery Pedicle Screws Orthopedics and Sports Medicine Prospective Studies 030222 orthopedics biology Ceftriaxone Spinal infection General Medicine Middle Aged Staphylococcal Infections Anti-Bacterial Agents Staphylococcus aureus Vancomycin Female Surgical site infection medicine.drug Adult Methicillin-Resistant Staphylococcus aureus medicine.medical_specialty medicine.drug_class Local antibiotic Vancomycin Hydrochloride Gram-positive bacteria A prospective comparative study.- Acta orthopaedica et traumatologica turcica cilt.52 ss.289-293 2018 [Eren B. Karagöz G. Kitiş S. Özkan N. Korkut C. -The effectiveness of pedicle screw immersion in vancomycin and ceftriaxone solution for the prevention of postoperative spinal infection] Sepsis 03 medical and health sciences medicine Humans Surgical Wound Infection Aged Implant associated infections business.industry Antibiotic Prophylaxis medicine.disease biology.organism_classification Methicillin-resistant Staphylococcus aureus Prevent infection Surgery lcsh:RD701-811 business Prophylactic antibiotic 030217 neurology & neurosurgery |
| Zdroj: | Acta Orthopaedica et Traumatologica Turcica, Vol 52, Iss 4, Pp 289-293 (2018) |
| Popis: | Objective: The aim of this study was to evaluate the efficacy of the local application of vancomycin hydrochloride (HCl)–ceftriaxone disodium hemiheptahydrate onto implants before using them to prevent postoperative infection. Methods: The study included 239 patients (153 women and 86 men; mean age: 48.23 ± 16.77 years) who had thoracolumbar stabilization with transpedicular screws. All surgeries were performed by the same surgeon. Patients were divided into two groups. In the group 1 (n = 104), implants were bathed in a solution of local prophylactic antibiotics for 5 seconds just before implantation. In the group 2 (n = 135), implants were not bathed before implantation. Local antibiotics used in the study was effective against gram positive bacteria (including methicillin resistant Staphylococcus aureus) and gram negative bacteria. The rate of surgical site infection and wound healing time were compared between the groups. Results: A total of 10 patients (4.1%) had deep wound infection and 20 (8.4%) had superficial infection. The most common bacteria was Staphylococcus aureus. One patient died 21 days after the surgery because of sepsis. The wound healed in a mean of 9.66 ± 2.04 days in patients who had no infection and in 32.33 ± 19.64 days in patients with infection (p |
| Databáze: | OpenAIRE |
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